Formulasi Eau de Parfum Berbahan Dasar Minyak Atsiri Khas Sukabumi sebagai Repellent terhadap Aedes aegypti

Nia Yuniarti, Devi Indah Anwar, Lela Lailatul Khumaisah

Abstract


Minyak atsiri, selain digunakan sebagai repellent (penolak nyamuk) juga digunakan sebagai bahan parfum. Tanaman penghasil minyak atsiri yang banyak tumbuh di daerah Sukabumi di antaranya adalah kapulaga (Amomum cardamomum). Pada penelitian ini dibuat formulasi parfum berbahan dasar minyak atsiri khas Sukabumi yang dapat berfungsi ganda yaitu selain sebagai pewangi tubuh juga berfungsi sebagai repellent terhadap nyamuk Aedes aegypti yang merupakan vektor penyakit demam berdarah dengue. Tujuan dari penelitian ini adalah mengetahui tingkat kesukaan (hedonik) parfum, menganalisis komponen, evaluasi kualitas, uji keamanan, dan menganalisis formula parfum yang paling efektif sebagai repellent terhadap A. Aegypti. Parfum yang dibuat adalah Eau de Parfum F1, F2, dan F3dengan 3 variasi komponen bagian parfum yang berbeda dari minyak atsiri kapulaga (A. cardamomum), lemon (Citrus limon), sereh wangi (Cymbopogon winterianus), nilam (Pogostemon cablin), dan ekstrak vanili (Vanilla planifolia). Hasil uji hedonik terhadap warna, aroma, dan kesegaran menunjukkan F2 sebagai parfum yang paling disukai panelis. Minyak kapulaga mengandung 4 komponen utama yaitu 1,8-sineol, β-pinen, 3-sikloheksen-1-metanol, dan α-pinen. Berdasarkan analisis GC-MS parfum F1, F2, dan F3 menunjukkan adanya lebih dari 20 komponen penyusun, dengan komponen utama 1,8-sineol, limonen, β-pinen, sitronelal, dimetil asetal hidroksisitronelal, etil vanillin, δ-guaien, dan patchouli alkohol. Parfum F1, F2, dan F3 memenuhi standar kualitas SNI 16-4949-1998, tidak menimbulkan iritasi dan alergi, serta memiliki aktivitas repellent terhadap A. aegypti dengan daya proteksi tertinggi pada parfum yaitu > 90% selama 1 jam dan daya proteksi rata-rata 74.8% selama 6 jam.

Keywords


Eau de Parfum; Minyak atsiri; Kapulaga; Repellent; Aedes aegypti;

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References


World Health Organization, “Dengue and severe dengue,” 2022. https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue.

R. Lestari, “Upayakan PSN 3M dan G1R1J untuk Tanggulangi DBD,” 2022. https://diskes.jabarprov.go.id/informasipublik/detail_berita/eTN5UW9LTWJrakdQRHRMRU1OcERTUT09.

P. Yanuar F, Mara Ipa, Rina Marina, and Yuneu Yuliasih, “Status Resistensi Aedes aegypti dengan Metode Susceptibility di Kota Cimahi terhadap Cypermethrin,” Aspirator, vol. 3, no. 1, pp. 18–24, 2011.

D. W. Sumekar and W. Nurmaulina, “Upaya pengendalian vektor demam berdarah dengue, Aedes aegypti L. menggunakan bioinsektisida,” Majority, vol. 5, no. 2, p. 131, 2016.

M. S. Fradin and J. F. Day, “Comparative efficacy of insect repellents against mosquito bites,” New Engl. J. Med., vol. 347, no. 1, pp. 13–8, 2002.

G. Briassoulis, “Toxic encephalopathy associated with use of DEET insect repellents: A case analysis of its toxicity in children,” Hum. Exp. Toxicol., vol. 20, no. 1, pp. 8–14, 2001, doi: 10.1191/096032701676731093.

Y. Trongtokit, C. F. Curtis, and Y. Rongsriyam, “Efficacy of repellent products against caged and free flying Anopheles stephensi mosquitoes,” Southeast Asian J. Trop. Med. Public Health, vol. 36, no. 6, pp. 1423–1431, 2005.

S. D. Rodriguez, L. L. Drake, D. P. Price, J. I. Hammond, I. A. Hansen, and N. Liu, “The efficacy of some commercially available insect repellents for Aedes aegypti (Diptera: Culicidae) and Aedes albopictus (Diptera: Culicidae),” J. Insect Sci., vol. 15, no. 1, pp. 1–5, 2015, doi: 10.1093/jisesa/iev125.

N. P. Yadav et al., “A novel approach for development and characterization of effective mosquito repellent cream formulation containing citronella oil,” Biomed Res. Int., vol. 2014, 2014, doi: 10.1155/2014/786084.

J. J. Zhu et al., “Better than DEET Repellent Compounds Derived from Coconut Oil,” Sci. Rep., vol. 8, no. 1, pp. 1–12, 2018, doi: 10.1038/s41598-018-32373-7.

J. J. Zhu, “Better than DEET Repellent Compounds Derived from Coconut Oil,” vol. 8, doi: doi: 10.1038/s41598-018-32373-7.

T. M. Katz, J. H. Miller, and A. A. Hebert, “Insect repellents: Historical perspectives and new developments,” J. Am. Acad. Dermatol., vol. 58, no. 5, pp. 865–871, 2008, doi: 10.1016/j.jaad.2007.10.005.

J. Gokulakrishnan, E. Kuppusamy, D. Shanmugam, A. Appavu, and K. Kaliyamoorthi, “Pupicidal and repellent activities of Pogostemon cablin essential oil chemical compounds against medically important human vector mosquitoes,” Asian Pacific J. Trop. Dis., vol. 3, no. 1, pp. 26–31, 2013, doi: 10.1016/S2222-1808(13)60006-7.

B. K. Sukabumi, “Promosi Peluang Investasi Sektor Perkebunan,” 2016. https://investasi.sukabumikab.go.id/perkebunan.html.

P. Widiyaningrum, D. Candrawati, D. R. Indriyanti, and B. Priyono, “Repellent Activity of Waste Extract from Two Local Medicinal Plant Against Rice Weevil (Sitophilus oryzae),” Biosaintifika, vol. 11, no. 1, pp. 62–67, 2019, doi: 10.15294/biosaintifika.v11i1.17651.

L. L. Khumaisah, A. Juliansyah, Juanda, Suardi, and C. Suardi, “Potensi Pengembangan Minyak Atsiri Kapulaga Indonesia sebagai Diversifikasi Ekspor Kabupaten Sukabumi,” vol. 1, 2022, [Online]. Available: http://ejournal.upi.edu/jpi.

S. Songkro, M. Jenboonlap, M. Boonprasertpon, D. Maneenuan, K. Bouking, and N. Kaewnopparat, “Effects of Glucam P-20, Vanillin, and Fixolide on mosquito repellency of citronella oil lotions,” J. Med. Entomol., vol. 49, no. 3, pp. 672–677, 2012, doi: 10.1603/ME11141.

K. Atkovska, S. Kuvendziev, E. Mustafa, M. Marinkovski, P. Ghaffari, and K. Lisichkov, “Essential Oils as Green Repellents Against Mosquito Vectors,” Qual. Life (Banja Luka) - APEIRON, vol. 20, no. 1, pp. 51–60, 2021, doi: 10.7251/qol2101051a.

Kiswanto, L. N. Rahayu, and Wintah, “Pengolahan Limbah Cair Batik Menggunakan Teknologi Membran Nanofiltrasi di Kota Pekalongan,” J. Litbang Kota Pekalongan, vol. 17, pp. 72–82, 2019.

R. Hutagaol, “Formulation of air Freshener Gel with Carrageenan as Gelling Agent, Lemon Oil as Fragrance and Patchouli Oil as Binder,” Int. J. ChemTech Res., vol. 10, no. 4, pp. 207–212, 2017.

F. D. Mayangsari, Djati Wulan Kusumo, and Zurotul Muarifah, “Uji Karakteristik Fisik Dan Hedonik Dari Antiaging Sleeping Mask Dengan Ekstrak Kulit Buah Delima Merah,” J. Ilm. Manuntung, vol. 8, no. 2, pp. 302–310, 2022, doi: 10.51352/jim.v8i2.640.

[BSN] Badan Standardisasi Nasional, “SNI 16-4949-1998 Sediaan eau cologne, eau de toilette, eau de parfum,” 1998. https://akses-sni.bsn.go.id/viewsni/baca/8575.

D. A., “No Title,” pp. 272–289, 1966, [Online]. Available: http://www.thomson.com.

dan R. Eka Kartika Untari, “jurnaljamuindonesia,+JJI+Vol+3(2)-2,” Uji Fis. dan Uji Iritasi Sabun Antiseptik Kulit Daun Aloe vera Burm. f, vol. 3, pp. 55–61, 2018.

D. P. dan Pestisida, “Metode Standar Pengujian Efikasi Pestisida Rumah Tangga dan Pengendalian Vektor T.A,” 2012. .

T. M. Asnawi, P. N. Alam, H. Husin, and M. Zaki, “The application of vacuum redistillation of patchouli oil to improve patchouli alcohol compound,” IOP Conf. Ser. Mater. Sci. Eng., vol. 345, no. 1, 2018, doi: 10.1088/1757-899X/345/1/012024.

E. Sikora, M. Małgorzata, K. W. Kennard, and E. Lason, “Nanoemulsions as a form of perfumery products,” Cosmetics, vol. 5, no. 4, pp. 1–8, 2018, doi: 10.3390/cosmetics5040063.

R. C. Rowe, P. J. Sheskey, and M. E. Quinn, Handbook of Pharmaceutical Excipients. 2009.

Y. Shan, “Extraction Processes of Functional Components From Citrus Peel,” Elsevier, pp. 31–58, 2016, doi: 10.1016/b978-0-12-809785-4.00003-4.

W. T. Eden, D. Alighiri, E. Cahyono, K. I. Supardi, and N. Wijayati, “Fractionation of Java Citronella Oil and Citronellal Purification by Batch Vacuum Fractional Distillation,” IOP Conf. Ser. Mater. Sci. Eng., vol. 349, no. 1, 2018, doi: 10.1088/1757-899X/349/1/012067.

N. Sabulal and S. Baby, “Chemistry of Amomum essential oils,” J. Essent. Oil Res., vol. 33, no. 5, pp. 427–441, 2021, doi: 10.1080/10412905.2021.1899065.

D. P. Anonis, “Patchouly Oil, Absolute and Aroma Chemicals: Part I,” vol. 31, pp. 36–39, 2006.

S. Vijayalakshmi, X. Disalva, C. Srivastava, and A. Arun, “Vanilla-Natural Vs Artificial: A Review,” Res. J. Pharm. Technol., vol. 12, no. 6, p. 3068, 2019, doi: 10.5958/0974-360x.2019.00520.1.

L. R. Tambunan, “Isolasi dan Identifikasi Komposisi Kimia Minyak Atsiri dari Biji Tanaman Kapulaga (Amomum Cardamomum Willd),” J. Kim. Ris., vol. 2, no. 1, pp. 57–60, 2017.

I. G. dan P. Rahayu, “Formulasi dan Evaluasi Parfum Tipe Eau de Toilette (EDT) ‘Senarai Jingga,” J. Kesehat., vol. 12, no. 2, pp. 257–265, 2021, [Online]. Available: http://ejurnal.poltekkes-tjk.ac.id/index.php/JK.

R. Murugan and C. Livingstone, “Origin of the name ‘patchouli’ and its history,” Curr. Sci., vol. 99, no. 9, pp. 1274–1276, 2010.

A. F. Blank, “Chemical characterization of the essential oil from patchouli accessions harvested over four seasons,” Ind Crop. Prod, vol. 34, no. 1, pp. 831–837, 2011, doi: 10.1016/j.indcrop.2011.01.021.

W. Dhifi, S. Bellili, S. Jazi, N. Bahloul, and W. Mnif, “Essential Oils’ Chemical Characterization and Investigation of Some Biological Activities: A Critical Review,” Medicines, vol. 3, no. 4, p. 25, 2016, doi: 10.3390/medicines3040025.

A. K. Z. A. F. Tsabitah, M. S. H. Wahyuningsih, and D. A. A. Nugrahaningsih, “Optimasi Carbomer, Propilen Glikol, dan Trietanolamin Dalam Formulasi Sediaan Gel Ekstrak Etanol Daun Kembang Bulan (Tithonia diversifolia),” vol. 16, no. 2, p. 111, 2020, doi: doi: 10.22146/farmaseutik.v16i2.45666.

W. S. Leal, “Does Zika virus infection affect mosquito response to repellents?,” Sci Rep, vol. 7, 2017, doi: 10.1038/srep42826.

Y. G. Gillij, R. M. Gleiser, and J. A. Zygadlo, “Mosquito repellent activity of essential oils of aromatic plants growing in Argentina,” Bioresour. Technol., vol. 99, no. 7, pp. 2507–2515, 2008, doi: 10.1016/j.biortech.2007.04.066.

M. R. M. da Silva and E. Ricci-Júnior, “An approach to natural insect repellent formulations: from basic research to technological development,” Acta Trop., vol. 212, no. September 2019, p. 105419, 2020, doi: 10.1016/j.actatropica.2020.105419.

G. Paluch, J. Grodnitzky, L. Bartholomay, and J. Coats, “Quantitative structure-activity relationship of botanical sesquiterpenes: Spatial and contact repellency to the yellow fever mosquito, aedes aegypti,” J Agric Food Chem, vol. 57, no. 16, pp. 7618–7625, 2009.




DOI: http://dx.doi.org/10.17977/um0260v7i22023p007

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